Cyclophosphamide (CTX) Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE135997
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Purpose: To understand the molecular mechanisms underlying the CTX synergization with antibody therapies in resistant niche-specific organs and BM-resident tumors Humanized mice were treated with CTX or PBS. Two days post treatment, mouse and human macrophages in the spleen and bone were sorted and applied to RNAseq.
创建时间：
2021-01-11
