MS-based phosphoproteomic of cytarabine-treated FLT3-ITD cells
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https://www.omicsdi.org/dataset/pride/PXD038638
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资源简介：
ITD mutations in the FLT3 gene occur in the 30% of acute myeloid leukemia patients. The integration of ITD in the tyrosine kinase domain (TKD-ITD) of the FLT3 receptor has been shown to confer resistance to standard chemotherapy treatment. We applied state-of-the-art, high-sensitive, mass spectrometry (MS)-based (phospho)proteomics to investigate the molecular mechanisms underlying the sensitivity to cytarabine therapy in FLT3-ITD cells.
创建时间：
2023-07-20
