Histone deacetylase inhibition sensitizes TP53-mutated B-cell precursor acute lymphoblastic leukemia to chemotherapy
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE234091
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To determine how histone deacetylation inhibition synergizes with cytarabine, we performed RNA sequencing investigating which genes are affected in response to romidepsin, cytarabine or the combination Nalm6 and RCH-ACV cells were either left untreated or treated for 16 h 2 nM romidepsin, 200 nM Cytarabine or a combination of both drugs, after which mRNA is isolated and transcriptome analyzed
创建时间：
2025-06-04
