Gut MAGs Dataset

This study generated a high-quality metagenome-assembled genome (MAG) catalog from the gut microbiomes of 40 HIV-infected individuals and 17 healthy controls in Shenzhen, China. Utilizing deep shotgun metagenomic sequencing and rigorous MAG reconstruction (including quality control, assembly, binning, refinement, and dereplication), we aim to systematically characterize compositional and functional alterations of the gut microbiota in people living with HIV (PLWH). This dataset provides a crucial resource to uncover microbial signatures linked to chronic HIV infection and identify candidate taxa for potential therapeutic interventions, addressing a critical gap in current microbiome research in PLWH.