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WildR F7 murine gut microbiome metagenome-assembled genomes

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Zenodo2025-12-12 更新2026-05-26 收录
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Due to limitations in current experimental approaches, the physiological role of microbial interactions in a mammalian gut microbiome remains poorly understood. Thus, to explore the consequences of bacterial antagonism in this environment, we characterized a wild murine gut microbiome, WildR. This microbiome was initially obtained from wild mice and reconstituted in germ-free laboratory mice in 2017 (Rosshart, et al. 2017 Cell. PMID: 29056339). To identify the speices present in this community, which has since been propogated for multiple generations, we performed long and short-read metagenomic sequencing and assembled metagenome-assembled genomes using a hybrid assembly approach of the current F7 generation. These MAGs facilitated identification of the community composition along with systems involved in microbial interactions. MAG sequences are uploaded as fasta files or with annotations from Prokka as genbank files. Fasta files containing contigs for each genome: WildR-MAG-fasta.tar.gz (0.25 GB) Prokka-annotated MAGs: WildR-MAG-prokka-genbank.tar.gz (0.45 GB) Assembly metrics and taxonomic annotations for each MAG are also uploaded. Assembly metrics: Table1-WildR-MAG-metrics.xlsx (50 KB) Taxonomic annotation: Table1-WildR-MAG-metrics.tsv (230 KB)

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2025-12-12
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