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Crystal structure PTP1B complex with small molecule compound LZP-6

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal structure PTP1B complex with small molecule compound LZP-6 Descriptor: 4,4'-piperazine-1,4-diylbis{1-[3-(benzyloxy)phenyl]-4-oxobutane-1,3-dione}, Tyrosine-protein phosphatase non-receptor type 1 Authors: Zhang, Z.-Y, Liu, S, Zhang, L.-F, Yu, X, Xue, T, Gunawan, A.M, Long, Y.-Q. Deposit date: 2008-08-26 Release date: 2009-07-07 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors. J.Am.Chem.Soc., 130, 2008
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2008-08-26
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