Structural studies of macromolecular interactions relevant to infectious and metabolic diseases. Standard Proposal

The BAG is comprised of 7 independent groups that mainly work in macromolecular interactions relevant to infectious and metabolic diseases, Due to the limited space in this section we only indicate the title of each research line. Research line 1: June Ereno Orbea Title: Deciphering the structural details of the recognition mode of sialic acids by Siglec receptors. Research line 2 David Albesa-Jove Title: Structural studies of the Type VI Secretion System Effectors Research line 3: Beatriz Trastoy Title: Structural basis of antibody glycosylation in autoimmune diseases Research line 4: Aitziber Lopez Cortajarena Title: Structural characterisation of functional protein-based hybrid materials Research line 5 Luis Alfonso Martinez de la Cruz Title: Elucidation of the three-dimensional Structure of the CNNM-Interactome and the crystal structure of CBS from Toxoplasma gondii. Research line 6: Aitor Hierro Title: Manipulation of host membrane trafficking by pathogens Research line 7: Adriana Rojas Title: Structural Characterization of the interaction of Wnt-11 with a function-blocking antibody.