Crystal Structure of FabI from F. tularensis in complex with novel inhibitors based on the benzimidazole scaffold.
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Crystal Structure of FabI from F. tularensis in complex with novel inhibitors based on the benzimidazole scaffold. Descriptor: 1-(4-methoxy-3-methylbenzyl)-5,6,7,8-tetrahydro-1H-naphtho[2,3-d]imidazole, ACETATE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ... Authors: Mehboob, S, Boci, T, Brubaker, L, Santarsiero, B.D, Johnson, M.E. Deposit date: 2013-02-05 Release date: 2014-07-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI). Bioorg.Med.Chem.Lett., 25, 2015
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2013-02-05



