Using Foxp3.RFP Rag.GFP reporter mice, mature Tregs in the thymus were characterized by performing RNA sequencing on Rag.GFP– and Rag.GFP+ Tregs that were isolated from the thymus and Tregs isolated f

NIAID Data Ecosystem70

Single-cell TCR-RNA-seq of splenic Tregs

单细胞免疫组学

调节性T细胞研究

A single-cell TCR-RNA-seq dataset comprised of CD4+ Tregs from the spleen. Overall design: Pooled splenocytes from 4 female TCliB x TCRa+/- x Foxp3-RFP mice (5 weeks old) were used to sort CD4+Dump(B2

NIAID Data Ecosystem40

Human Regulatory T cells from Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood. Human Regulatory T cells from Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood

单细胞免疫组学

调节性T细胞研究

Single-cell RNA and TCR sequencing data from sorted Tregs in umbilical cord blood and adult peripheral blood, both pre- and post-expansion. Overall design: Single-cell profiles of Tregs (gene expressi

NIAID Data Ecosystem70

Human blood and mucosal regulatory T cells express activation markers and inhibitory receptors in inflammatory bowel disease

炎症性肠病免疫表型分析

调节性T细胞研究

Background: FOXP3+ regulatory T cells (Tregs) are critical for preventing intestinal inflammation. However, FOXP3+ T cells are paradoxically increased in the intestines of patients with the inflammat

NIAID Data Ecosystem50

A reversible KO model reveals therapeutic potentials of defective Tregs

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