Crystal structure of the PDE9A catalytic domain in complex with inhibitor 28
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Crystal structure of the PDE9A catalytic domain in complex with inhibitor 28 Descriptor: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, N-(4-methoxyphenyl)-N~2~-[1-(2-methylphenyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-L-alaninamide, ... Authors: Hou, J, Ke, H. Deposit date: 2012-08-07 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure-Based Discovery of Highly Selective Phosphodiesterase-9A Inhibitors and Implications for Inhibitor Design. J.Med.Chem., 55, 2012
创建时间:
2012-08-07



