Microtubules (MTs) are one of the major components of the cytoskeleton, involved in cell division, intracellular transport, cell motility, and cell shape. Precise control of the highly-frequent events
Mutations in the family of genes encoding the tubulin subunits of microtubules are associated with a spectrum of human brain malformations known as tubulinopathies. How these mutations impact tubulin
• This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 16551mM D2O. • Images were taken with an An