RNA interference (RNAi) is a mechanism for interfering with gene expression through the action of small, non-coding RNAs. We previously constructed a short-hairpin-loop RNA (shRNA) encoding library th
Abstract RNA interference (RNAi) is a powerful gene silencing technology, widely used in analyses of reverse genetics, development of therapeutic strategies and generation of biotechnological products
A. Guide sequences and their sources for each gene targeted in test 4[sh], 8[sh], 12[sh], 16[sh] clusters (top) and 39 nucleotide-long sequences selected as spacers to separate individual hairpins (bo
GPAM is well characterized in triglyceride synthesis, but has never been implicated in cancer. Our study report a role for GPAM in cell migration. Gene expression changes after GPAM silencing was inve