Results for the second real data example.

Multiplicity-adjusted p-values of the tests for relative effects with respect to disease groups for three different immune-relevant parameters based on the asymptotic χ2 multiple test (χ2) and the multiple permutation test (Perm) in combination with the closure principle. The multiplicity-adjusted p-value for parameter ℓ denotes the smallest significance level such that Hℓ′ is rejected for the actually observed data. The permutation test was carried out as a Monte Carlo permutation test employing 9,999 randomly chosen permutations of {1,…,N}, together with the identity permutation. Treg: number of regulatory T-cells, tTL: total number of T-cells, immunoCRIT: cellular ratio of immune toleranceResults for the second real data example.