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KRasG12C in complex with GDP and compound 2

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Protein Data Bank Japan2024-11-20 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7r0n
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资源简介:
KRasG12C in complex with GDP and compound 2 Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ostermann, N. Deposit date: 2022-02-02 Release date: 2022-04-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C. Cancer Discov, 12, 2022
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2022-02-02
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