Effect of neuronal primary cilia on axonal tract development

This experiment aims to study the impact of primary cilia signaling on transcriptional programs relevant to axonal development in the mouse cerebral cortex. Transcriptional profiling of telencephalon from Arl13b-/- mutants and wild type controls本实验旨在探究初级纤毛信号通路（primary cilia signaling）对小鼠大脑皮层（mouse cerebral cortex）中与轴突发育（axonal development）相关的转录程序（transcriptional programs）的影响。研究对来自Arl13b-/-突变体（Arl13b-/- mutants）与野生型对照（wild type controls）的端脑（telencephalon）开展了转录谱分析（transcriptional profiling）。