Deletion of the thyroid hormone-activating type 2 deiodinase rescues cone photoreceptor degeneration but not deafness in mice lacking type 3 deiodinase

Using Next-generation sequencing (NGS) to get the retinal transcriptome profiles (RNA-seq) for understanding gene regulations during retina development Retinal mRNA profiles from embryo day 16.5 to postnatal day 28 wild type (WT) mice were generated by NGS sequencing本研究通过下一代测序（Next-generation sequencing, NGS）获取视网膜转录组谱（RNA-seq），旨在解析视网膜发育过程中的基因调控机制；所用数据集包含野生型（Wild type, WT）小鼠胚胎第16.5天至出生后第28天的视网膜mRNA表达谱，均由NGS测序构建得到。