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Iron-Dependent KDM4D Activity Controls the Quiescence-Activity Balance of MSCs

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1026566
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资源简介:
iron deficiency significantly dampened KDM4D demethylase activity, resulting in heightened enrichment of H3K9me3 in the promoter region of the PIK3R3 gene and subsequently reducing gene expression. Consequently, the activation of quiescent MSCs was hindered by the PI3K-Akt-Foxo1 pathway.
创建时间:
2023-10-10
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