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MethylationEPIC array of DNMT1 inhibitor treated AML cell lines - part II. MethylationEPIC array of DNMT1 inhibitor treated AML cell lines - part II

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NIAID Data Ecosystem2026-03-11 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA557722
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资源简介:
Genome wide demethylation by DNMT1 inhibitor GSK3484862 results in up-regulation of epigenetically-silenced genes. Methylation was assayed for each cell line following DNMT1 inhibitor or vehicle treatment. Global methylation distributions were compared between treated and untreated samples. Overall design: Seven AML cell lines were treated for 96 hours in biological duplicate with 0.1% DMSO or 1 µM GSK3484862 before isolating gDNA, labeling, and hybridizing to MethylationEPIC arrays.
创建时间:
2019-07-31
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