Cu-Catalyzed Direct C6-Arylation of Indoles
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https://figshare.com/articles/dataset/Cu-Catalyzed_Direct_C6-Arylation_of_Indoles/3473528
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资源简介：
The
first example of direct and site-selective arylation of indoles
at the C6 position has been reported. The key to this high regioselectivity
is the appropriate choice of the N–P(O)tBu2 directing group and the use of diaryliodonium
triflate salts as the coupling partners in the presence of catalytic
CuO. The protocol is distinguished by mild reaction system that avoids
ligand and additives, exhibiting wide scope of indole and arene coupling
components without compromising its efficiency and scalability, thus
representing a significant advancement in the implementation of regioselective
direct arylation of indoles.
创建时间：
2016-07-15
