Methylome of of HepG2 cells uninfected ("Cont") or infected with the pathogen Listeria monocytogenes ("Inf") by Methyl-binding domain-sequencing (MBD-Seq/MethylCap-Seq)

We report the partial methylome (CG-rich regions) of human hepatocytes (HepG2) infected or not by the bacterium Listeria monocytogenes Overall design: We used MBD-seq (MethylCap-Seq) to identify genomic regions differentially methylated after 3 days of infection with GFP-expressing Listeria. Infected and uninfected cells were purified by FACS prior to DNA extraction.