Develop an EGFR mutation gene expression signature to aid in predicting response and clinical outcome and to identify genes associated with the EGFR-dependent phenotype 17 primary lung adenocarcinomas
Mutations (including Missense point mutations/deletion/insertion) frequencies in 45 genes (737 loci) of lung cancer patients at different stagings according to AJCC staging.
1Total number of mutations: EGFR, n = 1627; TP53, n = 2387. 2The number of singlets, doublets and multiplets in EGFR is 1526, 98 and 5, respectively 3The number of singlets, doublets and multiplets in
ETV6::FRK is a rare kinase-related fusion gene which was identified only in AML but not in ALL. Herein, we firstly identified ETV6::FRK fusion gene in a patient with pediatric B-ALL. Because FRK is Sr
Develop an EGFR mutation gene expression signature to aid in predicting response and clinical outcome and to identify genes associated with the EGFR-dependent phenotype 17 primary lung adenocarcinomas
