Text S1 - Inferring Genome-Wide Recombination Landscapes from Advanced Intercross Lines: Application to Yeast Crosses

Details of isolation and sequencing of individual segregants, calling of segregating sites, and genotyping from sequencing data. Discussion of the potential to incorporate other breeding designs to the inference method. Details of crossing simulations, including results from use of the infinite population size approximation with small populations. Details of the recovery of known associations with recombination rate. Decay or recombination rate close to hotspots, and congruence between the crosses. Genome-wide reproductions of landscapes inferred for each of the crosses. Figures S1 to S9 are contained within Text S1. (PDF)