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CpG underrepresentation and the new bacterial CpG specific DNA methyltransferase M.MpeI

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NIAID Data Ecosystem2026-03-11 收录
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The CpG depleted Mycoplasma penetrans harbors a CpG specific C5 methyltransferase. The aim of this experiment was to confirm the specificity of the methyltransferase in vivo and in vitro. Overall design: Genomic DNA from Mycoplasma penetrans and Escherichia coli genomic DNA that either was or was not methylated in vitro by M.MpeI were subjected to Illumina MiSeq bisulfite sequencing.

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2019-09-23
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