Effects of KD USF2 on gene expressions in C2C12

USF2 has emerged as a key player in various cellular processes, including cell cycle regulation, apoptosi, metabolism, and response to cellular stress. In the context of muscle biology, the role of USF2 is not clear. To elucidate the functional significance of USF2, we conducted knockdown (KD) experiments targeting USF2 in C2C12 myoblast cells. The KD of USF2 resulted in the differential expression of a set of genes, and functional enrichment analysis of genes affected by KD of USF2 were performed. Overall design: To investiage the function of USF2 in C2C12 cells, expression profiling of genes affetcted by knocking donwn USF2 were evaluated by high throughput sequencing