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Novel players in myogenesis identified by target validation for muscle specific microRNAs in C2C12 myoblasts

ChEBI2012-07-22 更新2026-07-21 收录

肌生成调控

microRNA靶标

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-34069 数据链接链接失效反馈

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资源简介：

Novel players in myogenesis identified by target validation for muscle specific microRNAs in C2C12 myoblasts

应用场景：

创建时间：

2012-07-22

肌肉炎症

肌生成调控

Abstract Aim: To investigate the consequences of chronic eccentric exercise in histopathology, inflammatory, and myogenic regulatory factors response in gastrocnemius muscle of X-chromosome-linked mus

DataCite Commons2021-03-25 更新90

HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA. HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA

肌生成调控

转录后调控

Our study delineates a novel mechanism for HuR-mediated posttranscriptional regulation of myogenesis that requires its association to YB1 and provides new insights into the central role of posttranscr

NIAID Data Ecosystem40

Sumoylation-deficient phosphoglycerate mutase 2 impairs myogenic differentiation

肌生成调控

SUMO化修饰

To investigate the importance of functional regulation of PGAM2 by SUMO conjugation in the context of myogenic differentiation. We performed RNAseq analysis of WT and sumoylation deficient mutant (K17

NIAID Data Ecosystem20

Transcriptome wide target profiling for miR-199a-5p and miR-424-3p.

microRNA靶标

细胞周期调控

Whole transcriptome Identification of direct targets of miR-199a-5p and miR-424-3p using biotinylated pull-downs found that both miRNAs are likely to have a role in the cell cycle. HEK293T cells were

NIAID Data Ecosystem60

mRNA-seq in siNC and siCNN3 C2C12 cells. mRNA-seq in siNC and siCNN3 C2C12 cells

肌生成调控

基因沉默转录组

We evaluate the effects of CNN3 on myogenesis and further explored its potential molecular mechanisms. C2C12 cells were transfected with siRNA CNN3 and its NC control siRNA. Total mRNA was extracted f

NIAID Data Ecosystem40

Novel players in myogenesis identified by target validation for muscle specific microRNAs in C2C12 myoblasts

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