Data related to "Upper cortical layer-driven network impairment in schizophrenia" paper, by Batiuk, Tyler et al.

Zenodo2022-08-09 更新2026-04-07 收录

精神分裂症神经机制

空间转录组学

数据链接：

https://zenodo.org/record/5810785 数据链接链接失效反馈

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资源简介：

This is Data for "Upper cortical layer-driven network impairment in schizophrenia" paper, by Batiuk, Tyler et al., 2022 This repository contains: Supplementary Dataset Tables 1-4 (Supplementary_Dataset_Tables_1-4.xlsx). They contain DE genes and GO terms from snRNA-seq and visium analysis. Single nuclei and Visium spatial transcriptomics sequencing data (snRNA-seq_and_spatial_transcriptomics.zip) containing raw count matrices of snRNA-seq samples; Conos object with aligned snRNA-seq samples; snRNA-seq single nuclei cell subtype annotations; raw count matrices of Visium spatial transcriptomics samples; Visium spatial transcriptomics manual histological cortical layer annotations; and 10x Genomics spaceranger count pipeline output for Visium spatial transcriptomics data. Histological images of H&E stained Visium spatial transcriptomics samples mounted on visium slide capture area (visium_sample_images.zip)

提供机构：

EPFL, Lausanne, Switzerland; Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary; Croatian Institute for Brain Research & Center of Excellence for Basic, Clinical and Translational Neuroscience, School of Medicine, University of Zagreb, Zagreb, Croatia; Garcia-Gonzalez, Diego; Erzsebet Frank; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA; St. Petersburg Polytechnical University, St. Petersburg, Russia; BRIC, Copenhagen University, Denmark; Shenglin Mei; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA; Biotech Research and Innovation Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark; Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary;; Semmelweis University, Budapest, HU; Endocrinology Research Centre, Moscow, Russia

创建时间：

2022-08-09