Antibody derived (Abd-8) small molecule binding to KRAS.
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Antibody derived (Abd-8) small molecule binding to KRAS. Descriptor: 4-(2,3-dihydro-1,4-benzodioxin-5-yl)-~{N}-[3-[(dimethylamino)methyl]phenyl]-2-methoxy-aniline, GTPase KRas, MAGNESIUM ION, ... Authors: Bery, N, Cruz-Migoni, A, Quevedo, C.E, Phillips, S.V.E, Carr, S, Rabbitts, T.H. Deposit date: 2017-12-07 Release date: 2018-08-08 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions. Elife, 7, 2018
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2017-12-07
