Dimethylmonothioarsenate (DMMTA) is highly toxic for plants and induce strong transcriptome changes.

Arsenic is one of the most relevant environmental pollutants and human health threats. Several arsenic species occur in soil pore waters. Recently it was discovered that these include inorganic and organic thioarsenates. Dimethylmonothioarsenate (DMMTA) belong to organic thioarsenates and in mammalian cells its toxicity was found to exceed even that of arsenite. We investigated DMMTA toxicity in Arabidopsis thaliana (Col-0) and we found strong transcriptome changes dominated by stress-responsive genes. Overall design: RNA-seq anlysis of Arabidopsis thaliana (ecotype Col-0) seedlings exposed (treated) or not exposed (control) for 6h to 15 µM DMMTA.