KSDM1b Role in Ewing Sarcoma

NIAID Data Ecosystem2026-03-11 收录

尤文肉瘤分子机制

表观遗传调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE126275 数据链接链接失效反馈

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资源简介：

This study looks at the transcriptional profile of LSD2 knockdown in A673 Ewing sarcoma cells. RNA-seq data for A673 cells infected with retroviral vector expressing shRNA for Luciferase or KDM1b. 2 biological replicates were performed.

创建时间：

2019-08-29

DNA dioxygenases Tet2/3 control epithelial differentiation [RNA-seq]

毛囊上皮分化

表观遗传调控

Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes catalyzing 5-methylcytosine oxidation

Alliance of Genome Resources00

Genome-wide analysis of histone H3 acetylation levels of wild type, hda6, hdc1, and hda19 in short day conditions [ChIP-seq]

组蛋白H3乙酰化修饰

表观遗传调控

To investigate whether the expression of upregulated genes in hdc1 and hda19 is assoiated with histone acetylation levels increased in the hdc1 and hda19 mutants, We carried out ChIP-seq to examine hi

NIAID Data Ecosystem00

Mitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells. Mitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells

表观遗传调控

肾病与白血病基因功能研究

To examine if loss of FIS1 would alter the H3K27Ac status of leukemic cells, we used shRNA to knock down the expression of FIS1 in leukemic cell line MOLM-13 cells and performed H3K27Ac CHIP-seq to ch

NIAID Data Ecosystem00

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

Stage-specific Kdm6b-transcription factor partnerships orchestrate temporal precision during stepwise motor neuron differentiation [RNA-seq]

运动神经元

表观遗传调控

Histone modifiers instruct cellular differentiation, yet how they achieve temporal precision remains enigmatic. Here we demonstrate that the H3K27 demethylase Kdm6b acts as a master epigenetic conduct

NIAID Data Ecosystem00

KSDM1b Role in Ewing Sarcoma

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