Ranges of initial conditions (matching [5]) and the experimental noise (chosen as 1/2 the standard deviation of derivatives sampled from the long-time behavior of each species) for training data. In t
Perfusion parameters. ATT: traveling time from a labeling plane to an imaging slice, F: arterial flow parameter, δ: transit time from the arterial compartment to the capillary/tissue compartment in im
Kinetic models mechanistically link enzyme levels, metabolite concentrations, and allosteric regulation to metabolic reaction fluxes. This coupling allows for the quantitative elucidation of the dynam