Demonstrated and predicted alternative prominin-1 C-terminal domains‡.

‡Alternative splicing might generate ten distinct cytoplasmic C-terminal tails of prominin-1. Italics indicate predicted sequences, in the absence of protein data, for a given species.Complementary DNA; A, amphibian; C, chicken; D, dog; F, fish; H, human; M, mouse, R, rat, Rh, rhesus.Asterisk indicates that exon 25 introduces a frameshift on the following exon 26b. Double asterisk indicates that exon 27 in dog harbors a stop codon that would generate a truncated C-terminus in this species (MENGNIGFHRHHSTQTV). ND, not determined.References: 1, present study; 2, Yu et al. 2002; 3, Weigmann et al. 1997; 4, Corbeil et al. 2001; 5, Miraglia et al. 1997; 6, Miraglia et al. 1998; 7, Fargeas et al. 2004; 8, McGrail et al. 2010; 9, Fargeas et al. 2007; 10, Fargeas et al. 2003; 11, Canis lupus EST DT541441 and DT541268; 12, Mus musculus EST EH097137; 13, Pimephales promelas EST DT164241; 14, Xenopus tropicalis EST CX838199 and CX912260; 15, Xenopus leavis EST BJ061920; 16, Osmerus mordax EST EL532935, Pimephales promelas EST DT181633, Cyprinus carpio EST EX822056, Salmo salar EST DW541737; 17, Xenopus leavis EST CK796851.