MEK 1 kinase bound to G799
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4u80
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MEK 1 kinase bound to G799 Descriptor: 3-[(4-cyclopropyl-2-fluorophenyl)amino]-N-(2-hydroxyethoxy)furo[3,2-c]pyridine-2-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ... Authors: Ultsch, M.H, Robarge, K.D, Weismann, C. Deposit date: 2014-07-31 Release date: 2014-09-24 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479. Bioorg.Med.Chem.Lett., 24, 2014
创建时间：
2014-07-31
