Negative feedback regulation of miRNA processing enzymes by miRNA.

Note: The number of miRNA that bind to each mRNA was predicted using either microRNA.org using a threshold score of less than-0.10 or Diana-microT v3.0 with a threshold score of greater than 7.3. Diana-mirExtra was used to identify the miRNAs that were significantly downregulated on PAA (FC < -10, p< 0.05) from unregulated genes and used here to determine the proportion of predicted miRNA significant compared to the total miRNAs predicted for each miRNA processing gene. Negative feedback regulation of miRNA processing enzymes by miRNA.