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A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling]

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NIAID Data Ecosystem2026-03-12 收录
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Human iPS cells with different mutations linked to Alzheimer's Disease were differentiated into neurons and subjected to ribosome profiling to identify Alzheimer's Disease associated changes Ribosome profiling analysis of wildtype and three different mutated human iPS cells differentiated into neurons before

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2021-03-06
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