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Expression data from DP cells in the thymus of SRSF1-null and wild type mice

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP277007
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资源简介:
iNKT cells are highly conserved innate-like T lymphocytes that develop from CD4+CD8+ DP cells. It remains largely unknown whether post-transcriptional regulation has critical roles in iNKT cells. Here we show conditional deactivation of SRSF1 in DP thymocytes impaired iNKT cell development and survival in a cell-intrinsic manner. Overall design: WT and SRSF1-null CD4+CD8+ DP cells (2 samples per group) were sorted. Then the total RNAs were extracted and subjected to RNA sequencing.
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2022-11-22
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