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Gene expression profiling of D. melanogaster strains with varied resistance and tolerance to L. monocytogenes infection

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NIAID Data Ecosystem2026-03-10 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP064917
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资源简介:
We sequenced the mRNA of four D. melanogaster strains (w1118:BL6326, PBacCG2247:BL18050, PBacPCMT:BL18398, and RAL359:BL28131) during L. monocytogenes infection to determine the changes in gene expression dynamics responsible for resistance and tolerance phenotypes. Overall design: Examination of mRNA levels in groups of 20 adult males at 12 timepoints throughout infection and recovery. Flies were injected with 1000CFU of L. monocytogenes. On day 3 and onwards, flies were maintained on ampicillin supplemented food.
创建时间:
2017-09-17
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