five

Lactobacillus plantarum Zhang-LL inhibits colitis-related tumorigenesis

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP441958
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In this study, we constructed a mouse model of CRC using an intraperitoneal injection of azomethane combined with dextran sodium sulfate, while administering 5-fluorouracil as well as high- and low-doses of L. plantarum Zhang-LL live or heat-killed strains. To investigate the specific mechanisms involved in alleviating CRC progression, high-throughput sequencing technology was used to analyze the gut microbiota, non-targeted metabolomics of intestinal contents, and eukaryotic transcriptomics of intestinal tissues.
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2023-09-01
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