DNA mutations in somatic cells have been implicated in the causation of aging, with longer-lived species having a higher capacity to maintain genome sequence integrity than shorter-lived species. In a
ABSTRACT The objective of this study was to analyze the association of angiotensin-converting enzyme (ACE) I/D and alpha-actinin 3 (ACTN3) R/X genetics polymorphisms with functional capacity and fall
Background and Aims: Lifespan is influenced by complex interactions between genetic and environmental factors. Limitations in studying those factors in model organisms of a single genetic background h
This dataset contains genome-wide summary statistics (autosomal variants) computed from a multivariate genome-wide association study of five aging-related phenotypes using Genomic Structural Equation