EED in complex with PRC2 allosteric inhibitor EED162

EED in complex with PRC2 allosteric inhibitor EED162 Descriptor: 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED Authors: Zhao, K, Zhao, M, Luo, X, Zhang, H. Deposit date: 2016-10-08 Release date: 2017-01-25 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED PLoS ONE, 12, 2017