UCS1025A and B, New Antitumor Antibiotics from the Fungus <i>Acremonium</i> Species
收藏NIAID Data Ecosystem2026-03-06 收录
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UCS1025A and B, novel pentacyclic polyketides with an unprecedented furopyrrolizidine skeleton, were isolated from the fungus Acremonium sp. KY4917. The structures and stereochemistry were elucidated by a combination of two-dimensional NMR and X-ray crystallographic analysis. UCS1025A showed unique chemical equilibria involving three tautomeric isomers and exhibited antimicrobial activity and antiproliferative activity against human tumor cell lines.
创建时间：
2016-08-20
