Co-repressors Mtg8 and Mtg16 regulate niche exit and early fate decision of crypt stem cells

NIAID Data Ecosystem2026-03-11 收录

细胞命运决定

隐窝干细胞调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE124186 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2020-06-19

Stem cell fate choices are regulated through antagonistic control of lysosomes by MYC and TFEB [RNA-Seq 4]

细胞命运决定

蛋白酶体调控

We show that lysosomes are antagonistically controlled by TFEB and MYC to balance catabolic and anabolic processes required for activating LT-HSC and guiding their lineage fate. TFEB-mediated inductio

NIAID Data Ecosystem80

Single-Cell RNA-seq Transcriptome Profiling from Male Germ Cells Isolated from Late Fetal and Neonatal Mouse Testes

生殖细胞发育

细胞命运决定

To better understand the underlying dynamics driving formation of the spermatogonial stem cell (SSC) pool during development, we performed single-cell RNA-sequencing on mouse germ cells isolated from

NIAID Data Ecosystem60

Phosphorylated Groucho delays differentiation in the follicle stem cell lineage by providing a molecular memory of EGFR signaling in the niche

细胞信号传导

细胞命运决定

In the epithelial follicle stem cells (FSCs) of the Drosophila ovary, Epidermal Growth Factor Receptor (EGFR) signaling promotes self-renewal, whereas Notch signaling promotes differentiation of the p

DataONE2020-06-24 更新50

Sox5 Functions as a Fate Switch in Medaka Pigment Cell Development

细胞发育

细胞命运决定

Mechanisms generating diverse cell types from multipotent progenitors are crucial for normal development. Neural crest cells (NCCs) are multipotent stem cells that give rise to numerous cell-types, in

Figshare2016-01-18 更新60

An integrated global regulatory network of hematopoietic precursor cell self-renewal and differentiation

造血干细胞调控

细胞命运决定

The mammalian blood system is a hierarchically structured tissue. Hematopoietic stem cells (HSC) reside at the top of this hierarchy and the HSC-derived progenitor cells (HPC) have capacities for both

NIAID Data Ecosystem60

Co-repressors Mtg8 and Mtg16 regulate niche exit and early fate decision of crypt stem cells

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