首页/数据集/A toggle-switch between miR-142 and LIF-signaling creates heterogeneity among mouse ES cells. A toggle-switch between miR-142 and LIF-signaling creates heterogeneity among mouse ES cells

A toggle-switch between miR-142 and LIF-signaling creates heterogeneity among mouse ES cells. A toggle-switch between miR-142 and LIF-signaling creates heterogeneity among mouse ES cells

NIAID Data Ecosystem2026-03-09 收录

干细胞异质性

miRNA功能机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJEB6966 数据链接链接失效反馈

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资源简介：

miRNA sequencing in mouse embryonic stem cells according to miR-142 reporter activity

应用场景：

创建时间：

2016-01-01

乳腺癌放射抵抗

miRNA功能机制

Through the use of antagomiR-122, the knockdown of miR-122 was achieved with an efficiency of 70% in the cell line MCF-7RR with phenotype of acquired resistance to ionizing radiation. To evaluate the

NIAID Data Ecosystem90

Epigenetic Memory Underlies Cell Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

干细胞异质性

表观遗传记忆

Stem cells determine homeostasis and repair of many tissues and are increasingly recognized as functionally heterogeneous. To define the extent of and molecular basis for heterogeneity we overlaid fun

NIAID Data Ecosystem40

Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex. Homo sapiens

黑色素瘤分子机制

miRNA功能机制

The various roles of microRNAs (miRNAs) in controlling the phenotype of cancer cells are the focus of contemporary research efforts. We have recently shown that miR-17 directly targets the ADAR1 gene

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CD93+ and CD93- HSCs comparison [ATAC-Seq]. CD93+ and CD93- HSCs comparison [ATAC-Seq]

干细胞异质性

染色质可及性分析

Hematopoietic stem cells (HSCs) are characterized by their ability to generate all blood cells while retaining their self-renewal capacity. While it is convenient to believe that HSCs represent a homo

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Skeletal Stem Cell Diversity in Mouse Long Bones. Skeletal Stem Cell Diversity in Mouse Long Bones

干细胞异质性

单细胞RNA测序

We have used SmartSeq2 to sequence single phenotypic skeletal stem cell (SSCs) populations purified via FACS from adult mouse long bones. Two putative SSC populations were isolated based on their prev

NIAID Data Ecosystem20

A toggle-switch between miR-142 and LIF-signaling creates heterogeneity among mouse ES cells. A toggle-switch between miR-142 and LIF-signaling creates heterogeneity among mouse ES cells

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