Despite the importance of Aβ aggregation in Alzheimer’s disease etiology, our understanding of the sequence determinants of aggregation is sparse and largely derived from in vitro studies. For example
Neurons located in the layer II of the entorhinal cortex (ECII) are the primary site of pathological tau accumulation and neurodegeneration at preclinical stages of Alzheimer's disease (AD). Exploring
Differentially expressed proteins in the MSBB proteomics data set between AD cases and controls in the OL-enriched module (which has been randomly assigned the color name “Yellow”). (TSV 9 kb)
Detection of intron 3 and intron 12 retaining MAPT species by digital droplet PCR in frontal lateral cortex and hippocampal samples of non-demented individuals and Alzheimer's disease patients. Each r
