five

Transcriptome analysis in XACT deleted female human pluripotent stem cells

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141214
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In this study, we generated female human pluripotent stem cells with the deletion of large non-coding RNA XACT specifically expressed in human pluripotent stem cells. We obtained heterogenous knock out and compound null clones. In order to examine, the effect of XACT on X-linked genes expression states, we carried out allele specific expression analysis. Using CRISPR-Cas9 system, about 400Kb XACT gene regions are depleted in female human iPS cell (HPS002).
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2021-07-21
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