Figure 3 Panels

Immunohistochemical staining of CD47, B7-H3, and CD163. (A) High CD47 expression, evidenced by diffuse and intense membranous staining in epidermal and dermal tumor cells. (B) Low CD47 expression, showing limited membranous staining in epidermal and dermal tumor cells. (C) High B7-H3 expression, with strong cytoplasmic and membranous staining in tumor cells within both the epidermis and dermis. (D) Low B7-H3 expression, with weak membranous staining in the epidermis and dermis. (E) High CD163 expression, characterized by widespread cytoplasmic staining in tumor-associated macrophages in the dermis. (F) Low CD163 expression, with faint cytoplasmic staining in a small number of dermal macrophages. (CD47, B7-H3, CD163; DAB ×100).