Comparative transcriptome profiling to study the anticoccidial mechanisms of berberine in Eimeria acervulina infected chickens

Our previous study displayed that berberine treatment significantly reduced oocyst production in chickens infected with five different Eimeria species compared to untreated chickens, but there were differences in sensitivity to berberine. E. acervulina and E. praecox were generally the most sensitive species, whereas E. maxima was the least sensitive species (Nguyen et al., 2021). Of the most sensitive species E. acervulina is the most popular species in poultry industry (Lee et al., 2010; Flores et al., 2021). Thus, this study is carried out with E. acervulina-infected and berberine treated chickens.