RNA-sequencing study of global gene expression in haploid yeast Saccharomyces cerevisiae mating type MATa treated with different doses of alpha-pheromone

Yeast cells were treated with different doses of pheromone in order to obtain dose-response profiles for induced genes. Specifically, dose-dependencies of transcriptional feedback regulators of the pheromone-response pathway were quantified.为获取诱导基因的剂量反应谱，我们采用不同剂量的信息素（pheromone）处理酵母细胞。具体而言，本研究对信息素响应通路的转录反馈调控因子的剂量依赖性进行了定量表征。