File contains Figures A and B.

Figure A. Synthesis and structures of O-methylhonokiol derivatives. (A) Synthesis of aryl carbamate derivatives (GS12021 and c1~c5) from 4-O-methylhonokiol. (B) The structures of isoxazole derivatives (c6~c9) of 4-O-methylhonokiol. Figure B. The effect of GS12021 on iNOS protein stability. RAW 264.7 cells were incubated with LPS (10 ng/mL) for 6 h with or without pretreatment with GS12021 (20 μM) for 0.5 h, and then exposed to cycloheximide (CHX; 5 μg/mL) from 1 h to 4 h. Representative image of western blot analyses for iNOS expression. (DOCX)