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CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 15]

ChEBI2015-08-31 更新2026-07-12 收录

外泌体介导的细胞间通讯

白血病微环境

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-70995 数据链接链接失效反馈

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资源简介：

CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 15]

应用场景：

创建时间：

2015-08-31

白血病微环境

造血功能抑制机制

Acute lymphoblastic and myeloblastic leukemias (ALL and AML) have been known to modify the bone marrow microenvironment and disrupt non-malignant hematopoiesis. However, the molecular mechanisms drivi

NIAID Data Ecosystem70

The effect of bcCML leukemia progression on the bone marrow microenvironment

白血病微环境

单细胞RNA测序

Single Cell RNA-Sequencing was performed on CD45-Ter119- cells from leukemic mice at different stages of leukemic progression. Overall design: Bone and bone marrow from mice transplanted with bcCML le

NIAID Data Ecosystem40

β-catenin-controlled tubular cell-derived exosomes play a key role in fibroblast activation via the OPN-CD44 axis. β-catenin-controlled tubular cell-derived exosomes play a key role in fibroblast activation via the OPN-CD44 axis

纤维化机制

外泌体介导的细胞间通讯

Tubular injury and peripheral fibroblast activation are the hallmarks of chronic kidney disease (CKD) and renal fibrosis, suggesting intimate communication between the two diseases. However, the under

NIAID Data Ecosystem30

Cellular and exosome mediated molecular defense mechanism in bovine granulosa cells exposed to oxidative stress

生殖细胞氧化应激响应

外泌体介导的细胞间通讯

Various environmental insults including diseases, heat and oxidative stress could lead to abnormal growth, functions and apoptosis in granulosa cells during ovarian follicle growth and oocyte maturati

NIAID Data Ecosystem60

Adipose tissue mediate insulin resistance in obesity mice through the exosomal transfer of miR-141-3p into hepatocytes

外泌体介导的细胞间通讯

肥胖与胰岛素抵抗

Exosomes which are nano-vesicles and released from living cells, have attracted more attention as an important mediator for cell-to-cell communication. Given that obesity often causes insulin resistan

NIAID Data Ecosystem40

CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p [mirBase 15]

资源简介：

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