Adipose tissue adaptations to an 8-week weight loss intervention in younger and older obese men,

Abdominal subcutaneous adipose tissue transcriptomes were analyzed between 11 young and 8 elderly obese men during a lifestyle intervention. Lifestyle intervention: Individuals underwent 8-weeks of calorie-restriction of 20% below their daily energy requirement aerobic combined to two sessions of resistance exercise per weeks. Two groups,young and elderly; two conditions for each individual, baseline (before lifestyle intervention) and after lifestyle intervention.